Search results for "Antifungal Treatment"

showing 5 items of 5 documents

Dying with or because of invasive fungal infection? The role of immunity exhaustion on patient outcome

2016

De Rosa et al. considered clinical scores, biomarkers and their combination as useful aids for an early antifungal treatment and advocated the adoption of de-escalation therapy in an antifungal stewardship approach as a possible key for a better management of these patients. Authors considered the high burden of invasive fungal infections in terms of patient outcomes and costs and focused on current strategies for their optimization.

0301 basic medicineAntifungalmedicine.medical_specialtyEmergency Medicine; Anesthesiology and Pain Medicinebusiness.industrymedicine.drug_class030106 microbiology030208 emergency & critical care medicinemedicine.diseasesepsis fungal infectionOutcome (game theory)03 medical and health sciences0302 clinical medicineAnesthesiology and Pain MedicineAcquired immunodeficiency syndrome (AIDS)ImmunityAntifungal Treatment CORTEGIANI vs. DE ROSA: DEBATE Second RoundEmergency MedicineMedicineMED/41 - ANESTESIOLOGIAbusinessIntensive care medicine
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Should we administer antifungal drugs before the diagnosis of invasive fungal infection in non-neutropenic critically ill patients?

2016

0301 basic medicinemedicine.medical_specialtyEmergency Medicine; Anesthesiology and Pain MedicineCritically illbusiness.industryAntifungal drugsAntifungal Treatment CORTEGIANI vs. DE ROSA: DEBATE First Round030106 microbiologysepsis fungal infectionNon neutropenic03 medical and health sciencesAnesthesiology and Pain Medicine0302 clinical medicineEmergency Medicinemedicine030212 general & internal medicineMED/41 - ANESTESIOLOGIAIntensive care medicinebusiness
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Untargeted Antifungal Treatment Strategies for Invasive Candidiasis in Non-neutropenic Critically Ill Patients: Current Evidence and Insights

2017

Purpose of Review: The purpose of this study was to provide an overview and insights on important new concepts on untargeted antifungal treatment strategies, namely prophylaxis pre-emptive and empiric treatments for the management of invasive candidiasis (IC) in non-neutropenic critically ill patients. Recent Findings: Recently, clinical practice guidelines provided recommendation for the management of IC. However, results from recent trials and systematic reviews questioned the effect of untargeted antifungal treatment strategies, especially in terms of survival benefits in non-neutropenic patients, even with septic shock. Summary: Widespread use of untargeted antifungal treatment strategi…

Antifungalmedicine.medical_specialtyEmpiric treatmentmedicine.drug_classInvasive candidiasiBiology03 medical and health sciences0302 clinical medicineInvasive fungal infectionmedicine030212 general & internal medicineAntifungal treatmentMED/41 - ANESTESIOLOGIAIntensive care medicineCandida infectionCritically illCandidemia030208 emergency & critical care medicineInvasive candidiasismedicine.diseaseNon neutropenicClinical PracticeInvasive candidiasisInfectious DiseasesSystematic reviewTreatment strategyAntifungal treatment; Candida infection; Candidemia; Empiric treatment; Invasive candidiasis; Invasive fungal infectionEmpiric treatment
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What Is the Most Recent Evidence on the Prevention and Early Treatment of Invasive Fungal Infections in Nonneutropenic Critically Ill Patients?

2017

: Invasive fungal infections (IFIs) are associated with high morbidity and mortality in intensive care units. Candida species are the most important fungal pathogens and among the most frequent causes of infection in critically ill patients. Studies have evaluated the correlation between the onset of antifungal treatment and survival. However, definitive diagnosis of IFI is time-consuming in clinical practice. Antifungal prophylaxis and preemptive or empirical treatments are among therapeutic strategies to prevent or treat early fungal infections in selected patients. Recently, new evidence from randomized controlled trials and systematic reviews has been published. Moreover, new clinical p…

Antifungalmedicine.medical_specialtymedicine.drug_classFungal sepsisToxicologyCritical Care and Intensive Care Medicinelaw.invention03 medical and health sciencesHigh morbidityInvasive fungal infection0302 clinical medicineRandomized controlled triallawIntensive careMedicineAntifungal treatment030212 general & internal medicineIntensive care medicineCandida sppFungal sepsibusiness.industryCritically illPublic Health Environmental and Occupational Health030208 emergency & critical care medicineClinical PracticeAntifungal treatment; Candida spp; Fungal sepsis; Invasive fungal infectionInfectious DiseasesSystematic reviewFungal sepsisbusinessArchives of Clinical Infectious Diseases
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Antifungal Stewardship in Light of the Updated Evidence on Untargeted Antifungal Treatment in Critically Ill Patients

2016

Microbiology (medical)Antifungalmedicine.medical_specialtybusiness.industrymedicine.drug_classCritically illAntifungal TreatmentEarly InstitutionCochrane Systematic ReviewFungal InfectionSurgeryInfectious DiseasesMedical microbiologymedicineInvasive Fungal InfectionAntifungal Treatment; Cochrane Systematic Review; Early Institution; Fungal Infection; Invasive Fungal InfectionStewardshipIntensive care medicinebusiness
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